This is where breakthroughs break through.
The Ottawa Hospital’s Biotherapeutics Manufacturing Centre (BMC) — a not-for-profit cell and gene therapy CDMO focused on turning promising advanced oncology and rare disease research into clinically proven therapies — is now Boreal Biomanufacturing.
A rich history of manufacturing success.
Boreal is built on repeated success — on the production line, in patient rooms at The Ottawa Hospital, and out in the world.
This is where the hope that drives development of investigational products for cancer and rare disease is realized, through Phase I-III development and GMP-compliant production. It’s home to amazingly creative breakthroughs and incredibly disciplined manufacturing capabilities. And to a team of determined professionals working side-by-side with upwards of a thousand clinicians to give each patient something even better than hope: a tomorrow brighter than today.
Pioneered the development of oncolytic virotherapy treatments
Co-led development of the first made-in-Canada CAR-T therapy and public health infrastructure
Fostered the development and successful launch of multiple advanced therapy start-ups
Go from the seed of an idea to a fully realized product.
Phase I-III Contract Development & Manufacturing Experts
Boreal brings together translational expertise and deep early phase capabilities — as well as direct access to patients through a leading clinical centre conducting hundreds of active trials — to offer true bench-to-bedside capabilities, and streamline your efforts to turn research into care.
Our up-to-every-challenge manual and automated solutions for personalized cancer therapies deliver the product modality that works best for your innovation. We shine brightest in the development of investigational products, whether we’re delivering a single dose or thousands.
- Generation of material suitable for preclinical, toxicology studies and engineering batches
- Analytical/Microbiological method development
- Upstream/downstream manufacturing process development
- Vectored products, autologous and allogenic cell products, and cell lines
- Master cell and virus banks
- GMP-compliant Production for Investigational Products
- In accordance with Health Canada GUI-0001 & GUI-0119 and U.S Food and Drug Administration 21CFR210 and 21CFR211
- Testing of incoming raw materials for production
- Sampling and testing of GMP environmental and personnel monitoring
- GMP-compliant, product analytics testing
Boreal by the numbers
Work with people who’ve put in the work.
The Boreal Difference.
As unique as a fingerprint.
Every project — just like every cancer, and every patient — is unique. And our processes evolve to ensure we give our clients’ therapies every chance to succeed. The focus is always on results, and relentlessly working our way toward the best, most efficient way to achieve them.
As interconnected as the boreal forest.
You get the benefit of our deep roots: almost 20 years of insight, experience, and institutional knowledge. So you can count on getting expert guidance, making the right connections, and giving your advanced therapy the greatest chance to grow and thrive.
As dynamic as a living promise.
We take the trust you put in us seriously. At every step, we evaluate, strategize, and enhance — establishing the conditions for success, supporting the transition from preclinical development to first-in-human studies, and helping programs progress through rigorous clinical development.
Implausible missions welcome.
Our clients think big, no matter what size organization they come from. They have to — they’re pursuing the full promise of advanced therapies. They’ll entertain “no” only after every likely option (and all the unlikely ones) have been thoroughly exhausted.
Sound like you?
You’ll find a proven, fully engaged ally in Boreal.
We can help you advance complex therapies swiftly and strategically. We can take your inspired ideas and transform them into real-world breakthroughs. And we can do the most important thing of all: streamline the path from bench to bedside and speed the delivery of viable, clinically tested treatments.
Let’s work together to make things better.
You’ve got a game-changing idea to treat cancer or rare disease. We’re ready to bring it to life. Let’s get started.
